Publications
YTHDC2 control of gametogenesis requires helicase activity but not m6A binding
Saito Y, Hawley BR, Puno MR, Sarathy SN, Lima CD, Jaffrey SR, Darnell RB, Keeney S, and Jain D
Genes & Development 2022
YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis
Liu R, Kasowitz SD, Homolka D, Leu NA, Shaked JT, Ruthel G, Jain D, Lin H, Keeney, S, Luo M, Pillai RS, and Wang PJ
Cell Reports 2021
yama, a mutant allele of Mov10l1, disrupts retrotransposon silencing and piRNA biogenesis
Guan Y, Keeney S, Jain D*, and Wang PJ* (*co-corresponding authors)
PLoS Genetics 2021
shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination
Petrillo C, Barroca V, Ribeiro J, Lailler N, Livera G, Keeney S, Martini E*, and Jain D* (*co-corresponding authors)
Chromosoma 2020
Distinct 'safe zones' at the nuclear envelope ensure robust replication of heterochromatic chromosome regions
Ebrahimi H, Masuda H, Jain D, and Cooper JP
eLife 2018
RNAi drives nonreciprocal translocations at eroding chromosome ends to establish telomere-free linear chromosomes
Begnis M, Apte MS, Masuda H, Jain D, Wheeler DL, and Cooper JP
Genes & Development 2018
ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2
Jain D, Puno MR, Meydan C, Lailler N, Mason CE, Lima CD, Anderson KV, and Keeney S
eLife 2018
rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline
Jain D*, Meydan C, Lange J, Claeys Bouuaert C, Lailler N, Mason CE, Anderson KV, and Keeney S* (*co-corresponding authors)
PLoS Genetics 2017
A perfect palindrome in the Escherichia coli chromosome forms DNA hairpins on both leading- and lagging-strands
Azeroglu B, Lincker F, White MA, Jain D, and Leach DR
Nucleic Acids Research 2014
Telomeric strategies: means to an end
Jain D and Cooper JP
Annual Review of Genetics 2010
HAATI survivors replace canonical telomeres with blocks of generic heterochromatin
Jain D, Hebden AK, Nakamura TM, Miller KM, and Cooper JP
Nature 2010
H3 K36 methylation helps determine the timing of Cdc45 association with replication origins
Pryde F, Jain D, Kerr A, Curley R, Mariotti FR, and Vogelauer M
PLoS One 2009